Aldurazyme and cardiac failure Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5925624-1
Aldurazyme side effect was reported by a Health Professional from UNITED KINGDOM on Oct 02, 2008. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac failure. Aldurazyme dosage: unknown. Patient died.

Aldurazyme Side Effects Report #6133816-4
Aldurazyme side effect was reported by a Health Professional from UNITED KINGDOM on Feb 25, 2009. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac failure. Aldurazyme dosage: unknown. Patient died on 04/07/2006.

Aldurazyme Side Effects Report #6058364-1
Aldurazyme side effect was reported by a Physician from JAPAN on Jan 14, 2009. Male patient, 45 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac failure. Aldurazyme dosage: 14.5 MG,. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #6076393-9
Aldurazyme side effect was reported by a Physician from JAPAN on Jan 30, 2009. Female patient, 45 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac failure. Aldurazyme dosage: 14.5 MG. Patient was hospitalized. Patient recovered.


Aldurazyme Side Effects Report #5931881-8
Aldurazyme side effect was reported by a Physician from GERMANY on Oct 08, 2008. Female patient, 39 years of age, weighting 85.98 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: acute abdomen, cardiac failure, lymphadenectomy. Aldurazyme dosage: unknown. Patient recovered.

Aldurazyme Side Effects Report #5894609-6
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Sept 10, 2008. Male patient, 34 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: aspiration, cardiac failure. Aldurazyme dosage: 34.8 MG 1XW, INTRAVENOUS. Patient died on 09/09/2008.

Aldurazyme Side Effects Report #5894574-1
Aldurazyme side effect was reported by a Physician from BRAZIL on Sept 10, 2008. Female patient, 17 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac failure, disease progression. Aldurazyme dosage: 0.58 MG/KG, 1X/W, INTRAVENOUS. Patient died on 09/01/2008.

Aldurazyme Side Effects Report #5911529-9
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 18, 2008. Male patient, 34 years of age, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: arrhythmia , aspiration, blood immunoglobulin g increased, cardiac failure, pulmonary hypertension , sialoadenitis, vascular occlusion. Aldurazyme dosage: 34.8 MG, 1XW, INTRAVENOUS. During the same period patient was treated with OXYCONTIN, SERTRALINE, FLOVENT. Patient died on 09/09/2008.

Aldurazyme Side Effects Report #5776069-9
Aldurazyme side effect was reported by a Physician from PORTUGAL on May 30, 2008. Female patient, 18 years of age, weighting 70.55 lb, was diagnosed with mucopolysaccharidosis and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac failure, cardio-respiratory arrest, disease progression, pulmonary hypertension , respiratory failure. Aldurazyme dosage: unknown. During the same period patient was treated with FUROSEMIDE, ESPIRONOLACTONA. Patient died on 05/23/2008.