Aldurazyme and cardiac arrest Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5390725-6
Aldurazyme side effect was reported by a Physician from FRANCE on May 02, 2006. Male patient, child 4 years of age, weighting 35.94 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bradycardia, bronchial disorder, cardiac arrest , condition aggravated, disease progression, ear congestion, ear disorder, hypercapnia. Aldurazyme dosage: 14.5 MG QWK IV. During the same period patient was treated with VENTOLIN. Patient was hospitalized. Patient died on 03/17/2006.

Aldurazyme Side Effects Report #5036467-8
Aldurazyme side effect was reported by a Physician from FRANCE on June 09, 2006. Male patient, child 4 years of age, weighting 35.94 lb, was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bradycardia, bronchopneumonia, bronchopneumopathy, cardiac arrest , condition aggravated, disease progression, hypercapnia, mucopolysaccharidosis ih, obstructive airways disorder. Aldurazyme dosage: 14.5 MG QWK IV. During the same period patient was treated with VENTOLIN. Patient was hospitalized. Patient died on 03/17/2006.

Aldurazyme Side Effects Report #5397835-8
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on July 09, 2007. Female patient, child 9 years of age, weighting 49.82 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , ear infection staphylococcal, irritability, muscular weakness, staphylococcal skin infection. Aldurazyme dosage: 11.6 MG QWK IV. During the same period patient was treated with CIPRODEX, FLOXIN, BACTROBAN, SILVADENE. Patient died on 06/18/2007.

Aldurazyme Side Effects Report #5424872-7
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Aug 09, 2007. Female patient, child 9 years of age, weighting 49.82 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , condition aggravated, coronary artery stenosis, ear infection , fatigue, irritability, muscular weakness, skin infection, staphylococcal infection . Aldurazyme dosage: 11.6 MG QWK IV. During the same period patient was treated with CIPRODEX, FLOXIN, BACTROBAN, SILVADENE. Patient died on 06/18/2007.


Aldurazyme Side Effects Report #5390994-2
Aldurazyme side effect was reported by a Physician from UNITED STATES on Jan 06, 2006. Male patient, 30 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: atrioventricular block, cardiac arrest , cardiac pseudoaneurysm, intracardiac thrombus. Aldurazyme dosage: unknown. During the same period patient was treated with LASIX, COREG, ENALAPRIL MALEATE, WARFARIN, ADVAIR DISKUS, INSPRA, OXYGEN. Patient died on 12/03/2005.

Aldurazyme Side Effects Report #5390974-7
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Apr 02, 2007. Female patient, weighting 33.95 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: adrenal insufficiency, cardiac arrest , diarrhoea, disseminated intravascular coagulation, hypotension, septic shock, vomiting. Aldurazyme dosage: unknown. Patient died on 03/27/2007.

Aldurazyme Side Effects Report #5626938-5
Aldurazyme side effect was reported by a Health Professional from UNITED STATES on Feb 01, 2008. Female patient, weighting 24.91 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , convulsion, malaise, respiratory arrest. Aldurazyme dosage: 5.8 MG,QW,INTRAVENOUS. During the same period patient was treated with BENADRYL, ACETAMINOPHEN. Patient died on 10/31/2007.

Aldurazyme Side Effects Report #6125123-0
Aldurazyme side effect was reported by a Physician from UNITED STATES on Mar 04, 2009. Male patient, weighting 28.00 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute respiratory distress syndrome, bone marrow transplant , cardiac arrest . Aldurazyme dosage: 8.7 MG, 1X/W, INTRAVENOUS. Patient died on 01/15/2009.

Aldurazyme Side Effects Report #4971731-X
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 23, 2006. Male patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: abdominal distension, blood bilirubin increased, bone marrow transplant , cardiac arrest , convulsion, fluid overload, graft versus host disease in intestine, graft versus host disease in liver, graft versus host disease in skin. Aldurazyme dosage: 5.8 MG QWK IV. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient died on 02/15/2006.