Aldurazyme and bone marrow transplant Patient Reports February 12, 2012

Aldurazyme Side Effects Report #5390728-1
Aldurazyme side effect was reported by a Physician from CANADA on Jan 23, 2006. Female patient was diagnosed with mucopolysaccharidosis ih and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , haemolytic anaemia. Aldurazyme dosage: 1 MG/KG QWK IV. Patient died on 03/09/2005.

Aldurazyme Side Effects Report #5925624-1
Aldurazyme side effect was reported by a Health Professional from UNITED KINGDOM on Oct 02, 2008. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac failure. Aldurazyme dosage: unknown. Patient died.

Aldurazyme Side Effects Report #6133816-4
Aldurazyme side effect was reported by a Health Professional from UNITED KINGDOM on Feb 25, 2009. Female patient, child 5 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac failure. Aldurazyme dosage: unknown. Patient died on 04/07/2006.

Aldurazyme Side Effects Report #5925631-9
Aldurazyme side effect was reported by a Physician from UNITED KINGDOM on Oct 02, 2008. Female patient, child 4 years of age, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: acute graft versus host disease, bone marrow transplant . Aldurazyme dosage: unknown. Patient died.


Aldurazyme Side Effects Report #5892232-0
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2008. Male patient, child 2 years of age, weighting 26.46 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, bone marrow transplant , ear tube insertion, infusion related reaction, neutropenia, pyrexia. Aldurazyme dosage: 5.8 MG, 1X/W, UNK. Patient recovered.

Aldurazyme Side Effects Report #5390720-7
Aldurazyme side effect was reported by a Physician from CANADA on Nov 07, 2006. Male patient, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , cardiac valve disease, condition aggravated, deafness, hydrocephalus , kyphoscoliosis. Aldurazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Aldurazyme Side Effects Report #5390724-4
Aldurazyme side effect was reported by a Physician from NETHERLANDS on Mar 24, 2006. Female patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , graft versus host disease, transplant failure. Aldurazyme dosage: unknown. Patient died.

Aldurazyme Side Effects Report #6063766-3
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2009. Male patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: bone marrow transplant , malaise. Aldurazyme dosage: 8.7 MG, 1X/W, INTRAVENOUS. Patient died on 01/15/2009.

Aldurazyme Side Effects Report #6125123-0
Aldurazyme side effect was reported by a Physician from UNITED STATES on Mar 04, 2009. Male patient, weighting 28.00 lb, was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: acute graft versus host disease, acute respiratory distress syndrome, bone marrow transplant , cardiac arrest . Aldurazyme dosage: 8.7 MG, 1X/W, INTRAVENOUS. Patient died on 01/15/2009.


Aldurazyme Side Effects Report #4971731-X
Aldurazyme side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 23, 2006. Male patient was diagnosed with mucopolysaccharidosis i and was treated with Aldurazyme. After drug was administered, patient experienced the following side effects: abdominal distension, blood bilirubin increased, bone marrow transplant , cardiac arrest , convulsion, fluid overload, graft versus host disease in intestine, graft versus host disease in liver, graft versus host disease in skin. Aldurazyme dosage: 5.8 MG QWK IV. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient died on 02/15/2006.