Activacin and brain herniation Patient Reports February 12, 2012

Activacin Side Effects Report #5082955-8
Activacin side effect was reported by a Health Professional from JAPAN on Aug 09, 2006. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Activacin. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood creatinine increased, blood urea increased, brain herniation, brain oedema, cerebral artery embolism, depressed level of consciousness, haemorrhagic cerebral infarction. Activacin dosage: 38.4 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with RADICUT, ISOZOL, WARFARIN, PRIMPERAN ELIXIR, IMOVAN. Patient died on 03/11/2006.

Activacin Side Effects Report #5147082-X
Activacin side effect was reported by a Health Professional from JAPAN on Oct 31, 2006. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Activacin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arterial haemorrhage, aspartate aminotransferase increased, blood creatinine increased, blood urea increased, brain herniation, depressed level of consciousness, haemorrhagic cerebral infarction, liver disorder. Activacin dosage: 38.4 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with RADICUT, ISOZOL, WARFARIN, PRIMPERAN ELIXIR, GLYCEOL, MANNITOL, CEFAZOLIN, DOPAMINE HYDROCHLORIDE. Patient died on 03/11/2006.

Activacin Side Effects Report #4989342-9
Activacin side effect was reported by a Health Professional from JAPAN on Apr 20, 2006. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with Activacin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, arterial haemorrhage, aspartate aminotransferase increased, blood urea increased, brain herniation, brain oedema, haemorrhagic cerebral infarction, liver disorder, renal disorder. Activacin dosage: 42.4 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with RADICUT, ISOZOL, WARFARIN, PRIMPERAN ELIXIR, GLYCEOL, MANNITOL, CEFAZOLIN, DOPAMINE HYDROCHLORIDE. Patient died on 03/11/2006.