Abraxane and disease progression Patient Reports February 11, 2012

Abraxane Side Effects Report #5957428-8
Abraxane side effect was reported by a Physician from UNITED STATES on Nov 06, 2008. Female patient, 51 years of age, weighting 241.0 lb, was diagnosed with ovarian cancer and was treated with Abraxane. After drug was administered, patient experienced the following side effects: adenocarcinoma, blood pressure diastolic decreased, disease progression, hydronephrosis, hydroureter, intestinal perforation, lymphadenopathy, metastatic neoplasm, skin lesion. Abraxane dosage: unknown. During the same period patient was treated with AVASTIN, LISINOPRIL. Patient was hospitalized. Patient recovered.

Abraxane Side Effects Report #5804583-6
Abraxane side effect was reported by a Health Professional from UNITED STATES on July 07, 2008. Male patient, weighting 115.7 lb, was diagnosed with oesophageal adenocarcinoma and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, dysphagia. Abraxane dosage: 429 MG D1/CYCLE 042. During the same period patient was treated with VANDETANIB, ZEGARID, FENTANYL, LOVENOX. Patient was hospitalized. Patient recovered.

Abraxane Side Effects Report #5977644-9
Abraxane side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 01, 2008. Male patient, 76 years of age, weighting 137.9 lb, was diagnosed with non-small cell lung cancer and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, electrocardiogram p wave abnormal, fatigue, hypotension, supraventricular tachycardia. Abraxane dosage: 100MG/M2 IV D1 Q 21 D. During the same period patient was treated with CARBOPLATIN, AVASTIN, ATENOLOL, GLYBURIDE, PRILOSEC, ACETAMINOPHEN, OXYCODONE, OXYCODONE CONTROLLED RELEASE. Patient was hospitalized. Patient recovered.

Abraxane Side Effects Report #4807698-4
Abraxane side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 07, 2005. Female patient, 56 years of age, was diagnosed with malignant neoplasm progression and was treated with Abraxane. After drug was administered, patient experienced the following side effects: cardiac failure congestive, clostridial infection, disease progression, enterococcal infection, hypoxia, respiratory failure, small intestinal obstruction, staphylococcal bacteraemia, ventricular dysfunction. Abraxane dosage: INITIAL DOSE 176 MG, LAST DOSE 179 MG, 3 CYCLES 9 DOSES; INTRAVENOUS DRIP. Patient was hospitalized and became disabled. Patient recovered.


Abraxane Side Effects Report #6137270-8
Abraxane side effect was reported by a Health Professional from UNITED STATES on Mar 26, 2009. Male patient, 41 years of age, weighting 135.8 lb, was diagnosed with malignant melanoma and was treated with Abraxane. After drug was administered, patient experienced the following side effects: ascites, breath sounds abnormal, disease progression, facial wasting, hepatomegaly, oedema peripheral, oxygen saturation decreased, pleural effusion. Abraxane dosage: 170MG EVERY WEEK X 3 IV. During the same period patient was treated with SORAFENIB. Patient died on 02/08/2009.

Abraxane Side Effects Report #5804581-2
Abraxane side effect was reported by a Health Professional from UNITED STATES on July 07, 2008. Female patient, weighting 116.4 lb, was diagnosed with gastric cancer and was treated with Abraxane. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, disease progression, dyspnoea, hilar lymphadenopathy, localised intraabdominal fluid collection, lymphadenopathy mediastinal, nausea , pleural effusion. Abraxane dosage: 123 MG D1,D8,D15/CYCLE 042. During the same period patient was treated with VANDETANIB, ALDACTONE, LASIX, VICODIN, TYLENOL, ATARAX. Patient was hospitalized. Patient recovered.

Abraxane Side Effects Report #6013778-0
Abraxane side effect was reported by a Health Professional from UNITED STATES on Dec 18, 2008. Male patient, weighting 255.7 lb, was diagnosed with gastric cancer and was treated with Abraxane. After drug was administered, patient experienced the following side effects: decreased appetite, disease progression, haematemesis, retching, weight decreased. Abraxane dosage: 200 MG D1,D8, D15/CYCLE Q42. During the same period patient was treated with VANDETANIB, METFORMIN, EFFEXOR, ACIPHEX, AMBIEN, VICODIN, MEGACE. Patient was hospitalized. Patient died on 12/14/2008.

Abraxane Side Effects Report #4685968-0
Abraxane side effect was reported by a Health Professional from on May 23, 2005. Female patient, 67 years of age, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, dysphonia, metastases to bone, vocal cord paralysis. Abraxane dosage: 6 DOSES; 2 CYCLES (100 MG/M2, EVERY WEEK X 3 WK THEN OFF 1 WEEK), INTRAVENOUS DRIP. During the same period patient was treated with COUMADIN, OXYCONTIN, ZOMETA. Patient recovered.

Abraxane Side Effects Report #4694762-6
Abraxane side effect was reported by a Health Professional from on June 09, 2005. Female patient, 67 years of age, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, dysphonia, vocal cord paralysis. Abraxane dosage: 6 DOSES; 2 CYCLES (100 MG/M2, EVERY WEEK X 3 WK THEN OFF 1 WEEK), INTRAVENOUS DRIP. During the same period patient was treated with COUMADIN, OXYCONTIN, ZOMETA. Patient recovered.


Abraxane Side Effects Report #5091565-8
Abraxane side effect was reported by a Health Professional from UNITED STATES on Aug 17, 2006. Female patient, 66 years of age, weighting 163.0 lb, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, aspartate aminotransferase increased, asthenia, blood albumin decreased, blood bilirubin increased, blood glucose increased, disease progression, fatigue, liver function test abnormal. Abraxane dosage: 470 MG ONCE (260 MG/M2,X1), INTRAVENOUS DRIP. During the same period patient was treated with VICODIN, XELODA, EFFEXOR, SOTALOL, LEVOTHYROXINE, DIGOXIN, ACTOS, ELAVIL. Patient was hospitalized. Patient died on 03/26/2006.

Abraxane Side Effects Report #5107994-X
Abraxane side effect was reported by a Health Professional from UNITED STATES on Sept 12, 2006. Female patient, 66 years of age, weighting 163.0 lb, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, disease progression, globulins increased, metastases to liver, mucosal inflammation, myalgia, oral candidiasis, pancytopenia, sepsis . Abraxane dosage: 470 MG ONCE (260 MG/M2, X 1), INTRAVENOUS DRIP. During the same period patient was treated with VICODIN, XELODA, EFFEXOR, SOTALOL, LEVOTHYROXINE, DIGOXIN, ACTOS, ELAVIL. Patient was hospitalized. Patient died on 03/26/2006.

Abraxane Side Effects Report #5108520-1
Abraxane side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 12, 2006. Female patient, 66 years of age, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, blood albumin decreased, blood glucose increased, disease progression, mucosal inflammation, oral candidiasis, pancytopenia, sepsis . Abraxane dosage: 470 MG ONCE (260 MG/M2, X 1). During the same period patient was treated with VICODIN, XELODA, VENLAFAXINE, SOTALOL, LEVOTHYROXINE, DIGOXIN, ACTOS, ELAVIL. Patient was hospitalized. Patient died.

Abraxane Side Effects Report #5286063-2
Abraxane side effect was reported by a Physician from UNITED STATES on Mar 17, 2007. Female patient, 63 years of age, weighting 170.9 lb, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: blood glucose increased, condition aggravated, disease progression, facial palsy, herpes simplex , neuropathy peripheral. Abraxane dosage: 400 MG DAY/EVERY 3 WEEKS 8 DOSES (220 MG/M2, EVERY 3 WEEKS), INTRAVENOUS DRIP. During the same period patient was treated with HORMONAL AGENTS, FENTANYL PATCH, LIPITOR, PRILOSEC, ACCUPRIL, ZOMETA, GLUCOPHAGE, GLYBURIDE. Patient recovered.

Abraxane Side Effects Report #5302524-1
Abraxane side effect was reported by a Physician from UNITED STATES on Mar 29, 2007. Female patient, 63 years of age, weighting 170.9 lb, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: blood glucose increased, condition aggravated, disease progression, facial palsy, herpes simplex , neuropathy peripheral. Abraxane dosage: 400 MG DAY/EVERY 3 WEEKS 8 DOSES (220 MG/M2,EVERY 3 WEEKS), INTRAVENOUS DRIP. During the same period patient was treated with HORMONAL AGENTS, FENTANYL PATCH, LIPITOR, PRILOSEC, ACCUPRIL, ZOMETA, GLUCOPHAGE, GLYBURIDE. Patient recovered.


Abraxane Side Effects Report #5533902-3
Abraxane side effect was reported by a Physician from UNITED STATES on Nov 14, 2007. Female patient, 49 years of age, weighting 151.9 lb, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, peripheral motor neuropathy, peripheral sensory neuropathy. Abraxane dosage: ONE DOSE (450 MG) PRIOR TO SAE ON ON 23-OCT-07 (260 MG/M2, Q 3 WKS.). During the same period patient was treated with TYKERB. Patient recovered.

Abraxane Side Effects Report #5533904-7
Abraxane side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2007. Female patient, 49 years of age, was diagnosed with breast cancer metastatic and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, peripheral sensorimotor neuropathy. Abraxane dosage: ONE DOSE (450 MG) PRIOR TO SAE ON ON. During the same period patient was treated with TYKERB. Patient recovered.

Abraxane Side Effects Report #5286073-5
Abraxane side effect was reported by a Health Professional from UNITED STATES on Mar 17, 2007. Female patient, 62 years of age, weighting 145.3 lb, was diagnosed with breast cancer , facial palsy and was treated with Abraxane. After drug was administered, patient experienced the following side effects: disease progression, facial palsy. Abraxane dosage: 430 MG DAY/EVERY 3 WEEKS/18 DOSES (EVERY 3 WEEKS), INTRAVENOUS DRIP. During the same period patient was treated with STEROID, ATENOLOL, EFFEXOR, BEXTRA, AMBIEN. Patient recovered.

Abraxane Side Effects Report #5820035-1
Abraxane side effect was reported by a Health Professional from UNITED STATES on July 18, 2008. Female patient, weighting 130.1 lb, was diagnosed with adenocarcinoma and was treated with Abraxane. After drug was administered, patient experienced the following side effects: cerebrovascular accident, disease progression, visual impairment. Abraxane dosage: 429 MG D1/EACH CYCLE 042. During the same period patient was treated with VANDETANIB, ASPIRIN, IBUPROFEN. Patient was hospitalized. Patient recovered.

Abraxane Side Effects Report #6022476-9
Abraxane side effect was reported by a Health Professional from UNITED STATES on Dec 21, 2008. Female patient, weighting 172.4 lb, was treated with Abraxane. After drug was administered, patient experienced the following side effects: aphasia , disease progression, dysphasia, hypoaesthesia, hypoaesthesia facial, metastases to central nervous system, postictal state. Abraxane dosage: 189 MG D1,D8,D15/CYCLE 042. During the same period patient was treated with VANDETANIB, ATENOLOL, EEMT ESTROGEN, HYDROCODONE BITARTRATE. Patient was hospitalized. Patient recovered.